精氨酸是医药、特医食品和饲料行业广泛应用的组成分或营养添加剂。本文采用二次剪切复乳化形成精氨酸微胶囊乳液，通过喷雾干燥制备固体微胶囊。通过光学显微镜、电镜、质谱成像、电子鼻、电子舌、热重分析、体外模拟消化等系列表征和检测方法，系统分析了精氨酸微胶囊的形态、性状和消化特性，并通过稳定性试验测试了其贮藏稳定性。研究结果表明双剪切乳化可形成稳定的W/O/W型精氨酸微胶囊乳液，喷雾干燥制备的微胶囊为圆球形，平均粒径41.36 μm，精氨酸负载量12.16 wt.%，主要分布于胶囊内部，包埋率为95.51%；外层水溶性壁材对精氨酸的氨味和苦涩味具有良好的掩味效果，且在模拟胃液30 min消化中较易崩解，使精氨酸缓释率达到93.14%；精氨酸微胶囊具有良好的稳定性，在室温条件下贮藏90d精氨酸保留率达到93.82%。该研究可为精氨酸微胶囊在实际的商业应用提供理论依据。

Arginine is widely utilized as a component or nutritional additive in the pharmaceutical, medical food, and feed industries. In this paper, arginine microencapsulated lotion was formed by double shearing and double emulsification, and a solid microcapsule was prepared by spray drying. The morphology, physicochemical properties, and digestion characteristics of arginine microcapsules were systematically analyzed through a series of characterization and detection methods such as optical microscopy, electron microscopy, mass spectrometry imaging, electronic nose, electronic tongue, thermogravimetric analysis, and in vitro simulated digestion. The storage stability was investigated through a series of stability tests. The results showed that the double shear emulsification could form a stable W/O/W arginine microcapsule lotion. The microcapsule prepared by spray drying was round and spherical, with an average particle size of 41.36 μm, and the loading amount of arginine was 12.16 wt.%, which was mainly distributed inside the capsule, and the embedding rate was 95.51%; The outer water-soluble wall material exhibited good masking effects on the ammoniacal odor and bitterness of arginine. Additionally, it demonstrated a higher propensity for disintegration during the 30-minute simulated gastric juice digestion, resulting in a sustained release rate of 93.14% for arginine; Moreover, arginine microcapsules had good stability, with an arginine retention rate of 93.82% after 90 days of storage at room temperature. This study may provide a theoretical basis for the commercial application of arginine microcapsules in practice.