麦卢卡蜂蜜是产自新西兰的医疗级蜂蜜，具有独特的非过氧化抗菌活性，抗菌活性与其特征标志物有密切联系。随着国外学者对麦卢卡蜂蜜中抗菌活性物质的深入研究，其中的抗菌活性物质被不断地发现和证实，目前已发现的麦卢卡蜂蜜的特征标志物包括甲基乙二醛、3,5-二甲氧基苯甲酸甲酯-4-双葡萄糖苷、3-苯基乳酸、2-甲氧基苯乙酮、2-甲氧基苯甲酸、4-羟苯基乳酸、Lepteridine等，这些化合物也已应用于麦卢卡蜂蜜的质量评价和真伪鉴别中。麦卢卡蜂蜜在我国进口蜂蜜中所占的比重越来越大，但国内对麦卢卡蜂蜜的研究起步较晚，本文针对与麦卢卡蜂蜜质量评价及真伪鉴别相关的特征标志物及其分析方法进行了综述，以期为麦卢卡蜂蜜的质量评价和真伪鉴别研究提供参考。

Manuka honey is a medical grade honey from New Zealand, and has unique non-peroxide antibacterial activity. The antibacterial activity of manuka honey is closely related to its characteristic marker substances. With the increase of the number of in-depth studies on the antibacterial substances in manuka honey by foreign scholars, more and more antimicrobial substances have been found and confirmed in manuka honey. The characteristic markers of manuka honey that have been found so far include methylglyoxal, leptosperin, 3-phenyllactic acid, 2'-methoxyacetophenone, 2-methoxybenzoic acid, 4-hydroxyphenyllactic acid, lepteridine, etc. These compounds have also been used in quality evaluation and authenticity identification for manuka honey. Manuka honey accounts for an increasing proportion of imported honey into China, but the domestic study on manuka honey started relatively late. In order to offer a reference for quality evaluation and authenticity identification of manuka honey, this paper provides an overview of the marker substances characteristic for manuka honey and relevant to the quality evaluation and authenticity identification, together with their analysis methods.

国家重点研发计划项目（2017YFF0211000）