食品安全在世界卫生组织的定义是指所有食品中有毒、有害物质对人体健康影响的公共卫生问题。2008年“三聚氰胺”事件后，在近几年的全国两会上，食品安全问题连续成为焦点话题；而同期全国人大常委会通过的《食品安全法》，更显示了食品安全的严重与令人担忧，其监测与控制显得迫在眉睫。作为典型的食源性微生物,金葡菌尤其是耐甲氧西林金黄色葡萄球菌（Methicillin-resistant Staphylococcus aureus，MRSA）其新型的耐药特点显示了细菌耐药性的发展和进化可能是由于大量抗生素在畜牧业中的滥用而造成的。由于抗菌药物的研制周期跟不上耐药性出现的速度，使得细菌治疗面临越来越严峻的考验，甚至出现无药可用的情况，严重威胁人类健康。本文结合食品安全抗生素滥用问题与最近出现的超级细菌耐药问题，根据在相关领域多年的研究数据，对常见的食源性微生物MRSA及其检测方法在食品安全中的研究进展进行综述。

According to the World Health Organization, food security is a public health issue worldwide due to the presence of toxic and hazardous substances in food. After the melamine-tainted milk scandal in China in 2008, food security was a hot topic at subsequent sessions of the National People’s Congress and Chinese People’s Consultative Conference. At the same time, the Standing Committee of the National People's Congress passed the “Food Safety Law,” which states that the situation of food safety in China is serious and worrisome. Therefore, strengthening the monitoring and control procedures for food safety is an immediate concern. Staphylococcus aureus, especially methicillin-resistant S. aureus (MRSA) is a typical food-borne microorganism, exhibiting new drug-resistant characteristics, indicating that the development and evolution of bacterial drug resistance might be due to the misuse of antibiotics in livestock. Since the rate of developing new antibiotics cannot keep pace with the emergence of drug-resistance, treatment of bacterial infection is becoming more challenging. In situations where no effective antibiotics are available, human health is exposed to a serious threat. Combining the issues of food safety arising from antibiotic misuse and the recent drug resistance of “superbugs,” the authors present a review of research progress on the common food-borne microorganism MRSA and its detection methods for food safety.

国家自然科学基金青年基金项目（31201362）；中央高校基本科研业务费面上项目（2012ZM0060）