本文开展室温下微滤-超滤-纳滤多级膜浓缩黄芩苷提取液的研究，采用HPLC法测定了黄芩苷在不同膜过程的透过液和浓缩液中分布情况。研究结果表明：多级膜分离浓缩法可以除出黄芩苷提取液55%水分，黄芩苷的保留率为96%，浓缩比为2.4倍，在常温下多级膜浓缩分离黄芩苷提取液是可行的。

Multistage membrane processes, including microfiltration, ultrafiltration and nanofiltration, were used in the concentration of baicalin extracts at room temperature, and the concentrations of baicalin in the filtrated liquids and retentions in different membrane processes were determined with HPLC. The results showed that the water removal rate，the retention rate of baicalin and the concentration ratio were 55%, 96%, and 2.4 folds, respectively, which indicated that the method for baicalin concentration by multistage membrane was feasible at normal temperature.

十一五国家科技支撑计划课题（2006BAD05A02）；东莞市科技攻关项目（2006014）