目的 研究甘草菊花复方中甘草酸和总黄酮的联合提取工艺。方法 以甘草酸和总黄酮的提取率为指标，考察提取时间、提取温度、固液比和提取次数对甘草酸和总黄酮提取率的影响，并通过正交实验确定最适提取工艺。结果 优化的的甘草/菊花中甘草酸和总黄酮的联合提取工艺为：提取时间3 h，提取温度90 ℃，固液比1﹕12，提取次数2次。

Objective: To study the combined extraction techniques of glycyrrhizic acid and flavonoids from compound of licorice and chrysanthemum. Methods: The effects of extraction time, extraction temperature, the ratio of water to solid and extraction times on the extraction rate of glycyrrhizic acid and flavonoids were investigated. And the optimal extraction conditions were determined by orthogonal experiments. Results: The optimal combined extraction time, temperature, the ratio of water to solid and extraction times were 3 h, 90 ℃, 12:1 and 2, respectively.