目的：研究大孔吸附树脂分离纯化高良姜中高良姜素的工艺条件及参数。方法：以高良姜素的吸附率和解吸率为考察指标，从中筛选树脂，并研究大孔吸附树脂分离纯化高良姜素的吸附性能和洗脱参数。结果：HPD-600树脂对高良姜素有较好的吸附分离性能，适合于从高良姜中提纯高良姜素，经该树脂吸附解吸，饱和吸附率为91.8％，解吸率85.36％。结论：大孔吸附树脂分离纯化高良姜素的纯度可达92.4％，而上柱前初提物中高良姜素纯度为59.4％，说明采用本方法分离纯化高良姜素是可行的。

Objective: To study the purification process of galangin in Alpinia officinarum Hance with macroporous adsorptive resin. Methods: The static adsorption ratio and elution ratio were used to evaluate the adsorption performance of the tested resins for the separation and purification of galangin. Results: Resin HPD-600 showed good separation performance and was selected to purify galangin in Alpinia officinarum Hance. With this resin, the static adsorption ratio of galangin was 91.8% and the desorption ratio of galangin was 85.36%. Conclusion: The purity of the product was up to 92.4%, while it was just 59.4% before purification. This adoption of macroporous adsorption resin to adsorb and purify galangin in Alpinia officinarum Hance was feasible.

广东省科技攻关项目（2003C104025）；广东省关键领域重大突破项目（2003A30908）；广州市科技成果转化计划（2004C13G0231）