本文主要综述了近年来饲料基质中兽药含量的检测分析方法。简要介绍了关于兽药在饲料中使用的相关规定，以及添加使用兽药的用途和违禁使用兽药的危害。重点介绍了饲料中兽药含量检测的前处理技术和检测技术，包括样品的提取、分离、纯化和检测等，并分析了不同检测技术的优点和不足，以及不同检测技术在兽药检测中的应用。最后，讨论了饲料中兽药检测技术的发展前景与趋势。指出兽药品种多样、饲料基质复杂，在不同兽药的检测方法上存在差异，精确、快速和高通量的检测方法相对较少。需要优化兽药检测前处理技术，缩短前处理时间，提高检测效率；同时，加大力度研究和开发高灵敏度和准确度的检测技术，为更好的监督和规范饲料中兽药的使用提供可靠的依据。

The methods for the detection and analysis of veterinary drugs in feed in recent years were reviewed. A brief introduction on the relative laws and regulations regarding the usage of forage and medicine, as well as the advantages of using veterinary drugs and the harm of illegal uses of unsafe drugs in feed were summarized. Emphasis was laid on pretreatment technology and detection technology of feed matrices, including sample extraction and separation as well as purification and different detection methods, being in use for the determination of drugs. It is provided to illustrate common trends and method variability. The advantages and disadvantages of different detection techniques, as well as the application of different detection techniques in the detection of veterinary drugs were analyzed. Finally, the possibilities of novel analytical approaches were discussed. Due to the variety of the veterinary drug and the complex feed matrix, there are many differences in the detection methods of veterinary drugs. However, the exact, fast and high-throughput detection methods are relatively few. It is necessary to optimize the pretreatment technology, shorten pre-processing time and improve detection efficiency of veterinary drug detection, and intensify research and development of high-sensitivity and accuracy detection technology to provide a reliable basis for better supervision and regulation of the use of veterinary drugs in feed.

上海市科委科研项目(16142201500；17DZ2293700）；长三角科技合作项目（17395810102）；中央引导地方科技发展专项（YDZX20173100004528）