根据中心组合(Box-Behnken)试验设计原理，在单因素试验的基础上，采用四因素三水平的响应面分析法，对酸浆宿萼色素提取工艺进行优化。结果表明，酸浆宿萼色素提取的最佳工艺为液料比7:1、超声功率160 W、超声温度41 ℃、超声时间53 min。在此条件下得到色素得率为2.68%。

The response surface methodology based on single factor experiments and Box-Behnken design principle was used to optimize processing parameters of ultrasonic-assisted extraction for pigments from Physalis alkekengi L. Results showed that the optimal processing conditions of extraction were liquid/material ratio of 7:1 (mL/g), ultrasonic power of 160 W, ultrasonic temperature of 41 ℃, and ultrasonic time of 53 min. Under these conditions the pigment yield was 2.68%.