研究了不同血清型食源性单核细胞增生李斯特菌对重金属镉的抗性及其与抗生素耐药性之间的关系。采用琼脂稀释法检测单核细胞增生李斯特菌对重金属镉的抗性，与菌株的抗生素耐药性进行比较分析。结果表明，73株实验菌株中，36株具有镉抗性，总体镉抗性率达49.3%（36/73）。分离到的5株多重耐药单核细胞增生李斯特菌均为镉抗性菌株，表明食品生产、加工及其储存环境中这种同时携带多重耐药性与重金属抗性的微生物从食品链及有关环境进入到人类，就会对人类健康构成构成潜在威胁。

To determine the prevalence of cadmium resistance among food-borne Listeria monocytogenes isolates of different serotypes and to know whether there are possible associations between cadmium resistance and antibiotic resistance of these isolates, all isolates were tested for their resistance to cadmium by agar dilution method. Results showed that, among 73 isolates, 36 cadmium-resistant strains were detected, the overall resistance ratio was 49.3%（36/73）. Besides, the 5 multidrug resistant strains isolated in this study were all resistant to cadmium, indicating that in case of the involvement of Listeria monocytogenes with both cadmium and multidrug resistance in human disease, through food chains or environmental factors, the human health should be seriously threatened.

中央高校基本科研业务费资助项目(2012ZZ0083)；辽宁省食品安全重点实验室开放课题资助项目(LNSAKF2011002)；国家自然科学基金（31201363）；广州市科技计划项目（11C12080718）