食用菌蛋白质降血糖机制研究进展

Research Progress on the Hypoglycemic Mechanism in Edible Fungal Proteins

摘要:

糖尿病作为一种常见的代谢性和内分泌疾病，会引发多种严重并发症，影响患者的生存质量。尽管当前临床上有多种降血糖药物可供选择使用，但这些药物都存在或多或少的不良反应。近年来，随着对食用菌蛋白质研究的不断深入，其在降血糖方面的潜力逐渐受到科学界的关注。本文综述了食用菌蛋白质通过调节免疫、调节机体对葡萄糖的利用、调节胰岛素信号传导通路、减轻氧化炎症反应等途径调节糖代谢的机制原理，以期为糖尿病患者提供更为安全有效的治疗选择。

Abstract:

Diabetes mellitus is a common metabolic and endocrine disorder that can result in serious complications, affecting an individual’s quality of life. Although multiple hypoglycemic drugs are available for clinical use, they are all associated with varying degrees of adverse reactions. In recent years, research on edible fungal proteins has increased, and their potential for lowering blood sugar has garnered considerable attention from the scientific community. This review discusses the mechanisms by which edible fungal proteins regulate glucose metabolism, including the modulation of immunity, regulation of glucose utilization, modulation of insulin signaling pathways, and alleviation of oxidative inflammatory responses. This review findings provide guidance for the development of safer and more effective treatment options for patients with diabetes.