褐藻多糖的提取及生物活性研究进展

Research Progress on the Extraction and Biological activity of Polysaccharide from Brown Algae

摘要:

海洋来源的天然产物种类丰富，生物活性优良，在寻找新型治疗药物和保健功能品上具有巨大的潜力。褐藻是我国主要养殖的一类经济藻类，也是获取天然产物的良好来源。褐藻多糖是褐藻主要活性成分之一，由于其复杂的组分和结构，使其具有多种生物活性，如抗氧化、抗炎、免疫调节、抗肿瘤、抗菌、抗病毒、抗糖尿病等。因此，褐藻多糖的提取和活性研究成为海洋生物资源开发与利用领域的热点。本文就近5年来国内外有关褐藻多糖的提取方法及主要的生物活性研究进行综述，对比了各种提取方法的优劣，论述了褐藻多糖的生物学功能及作用机理，分析了可能相关的影响因素，并对目前和未来的褐藻多糖研究进行了总结与展望，以期为促进褐藻多糖的生产和应用提供参考。

Abstract:

Natural products from marine sources are rich in diversity and excellent biological activity, which have great potential in the search for new therapeutic drugs and functional health care products. Brown algae is a type of economic algae mainly cultivated in China, which is also a good source of natural products. Brown seaweed polysaccharide is one of the main active components of brown algae. Due to its complex components and structure, brown seaweed polysaccharide has a variety of biological activities, such as antioxidant, anti-inflammatory, immune regulation, anti-tumor, antibacterial, anti-virus, anti-diabetes, and so on. Therefore, the study of extraction and activity of brown seaweed polysaccharide has become a hot spot in the field of development and utilization of marine biological resources. In this paper, the extraction methods and main biological activities of brown seaweed polysaccharide at home and abroad in the past 5 years were reviewed, the advantages and disadvantages of various extraction methods were compared, and the biological function and action mechanism of brown seaweed polysaccharide were discussed. The possible influencing factors were analyzed, and the current and future research of brown seaweed polysaccharide was summarized and prospected, to provide a reference for promoting the production and application of brown seaweed polysaccharide.