该文建立了一种混酸体系-四级杆碰撞反应池-ICP/MS法（Inductively Coupled Plasma Mass Spectrometry，ICP/MS）测定含硅类食品添加剂中铅、砷的方法。样品用氢氟酸-盐酸-硝酸组成的混酸体系进行微波消解前处理，采用四级杆碰撞反应池-ICP/MS法进行铅、砷的同时测定，选取Pb208、As75作为测定目标元素，Bi209、Ge72做相应的内标元素，应用碰撞/反应池技术、氦气动能歧视（Kinetic Energy Discrimination，KED）模式进行分析检测。铅、砷在0.000 5~0.100 0 μg/mL范围内线性关系良好，r2均大于0.999。对样品进行加标回收验证，铅、砷的回收率分别为92.0%~107.0%和94.0%~104.0%，相对标准偏差（Relative Standard Deviations，RSDs）分别为2.49%、1.68%，铅、砷的检出限分别为0.003和0.002 mg/kg。该方法具有高的准确度、灵敏度、精密度和很小的干扰性等优点，适合测定含硅类食品添加剂中的铅、砷，可用来进行含硅类食品添加剂的质量监控和安全评价。

A mixed acid system-quadrupole collision reaction cell-ICP/MS (Inductively Coupled Plasma Mass Spectrometry, ICP/MS) method for determination of lead and arsenic in silicion-containing food additives was set up. Samples were pretreated by microwave digestion with a mixed hydrofluoric acid-hydrochloric acid-nitric acid system, then the lead and arsenic were simultaneously determined by the quadruple collision cell-ICP/MS method, with Pb208 and As75 as the target elements for determination, Bi209 and Ge72 as the corresponding internal standard elements, and the collision/reaction cell technology and helium kinetic energy discrimination (KED) mode for analysis and detection. Lead and arsenic had a good linear relationship in the range of 0.000 5~0.100 0 μg/mL with r2 greater than 0.999. The samples were subjected to standard addition recoveries experiments, and the spiked recoveries of lead and arsenic were 92.0%~107.0% and 94.0%~104.0%, respectively. The samples were spiked and recovered to verify that the recoveries of lead and arsenic were 2.49% and 1.68%, respectively. The detection limits of lead and arsenic were 0.003 mg/kg and 0.002 mg/kg, respectively. This method had advantages in terms of high accuracy, high sensitivity, high precision and little interference, which is suitable for the determination of lead and arsenic in silicon-containing food additives, as well as quality monitoring and safety evaluation of silicon-containing food additives.