平卧菊三七的化学成分及生物活性研究进展

Research Progress on Chemical Constituents and Biological Activities of Gynura procumbens

摘要:

平卧菊三七Gynura procumbens (Lour.) Merr是菊科菊三七属的一年生草本植物，又名蔓三七，在东南亚及我国广东、江西、贵州等地有广泛种植。平卧菊三七作为一种“药食同源”的植物在一些东南亚国家及我国民间已被广泛食用，其味辛性寒，具有活血化瘀，解毒散热等功效，且含有丰富的活性成分，包括黄酮类、酚类、生物碱、脂肪酸类、萜类及甾体类等化学成分，现代医学研究表明平卧菊三七具有抗氧化、抗炎、抗癌、降血糖、降压及护肝等多种生物活性，药用价值较高。该研究以国内外文献为参考依据，对平卧菊三七的根、茎、叶等不同部位的化学成分及生物活性的研究进展进行综述，以期为平卧菊三七药食同源新型保健产品的开发提供参考，为平卧菊三七资源的综合利用和进一步开发提供依据。

Abstract:

Gynura procumbens (Lour.) Merr, known as Man San Qi, is an annual herb belonging to the family Asteraceae and is widely distributed in Southeast Asia and several regions in China, including Guangdong, Jiangxi, and Guizhou. G. procumbens has been widely used as a “medicine and food homology” plant in folk medicine in China and some Southeast Asian countries. It is characterized by a bitter flavor and cold nature, which can be used to promote blood circulation and detoxification. G. procumbens is rich in bioactive constituents, including flavonoids, phenols, alkaloids, fatty acids, terpenoids, and steroids. Modern medical research has shown that G. procumbens has a high medicinal value with a wide variety of biological activities, such as antioxidation, anti-inflammation, anticancer, antihyperglycemia, antihypertension, and liver protection. With reference to domestic and foreign literature, this study summarized the research progress on the chemical constituents and biological activities of different parts of G. procumbens including its roots, stems, and leaves, to provide a reference for novel healthcare products based on the medicine and food homology of G. procumbens and a basis for the comprehensive utilization and further development of G. procumbens.