6-姜酚对幽门螺杆菌的抑菌作用研究

Anti- Helicobacter pylori effect of 6-gingerol in vitro

摘要:

探讨生姜中姜辣素的主要成分6-姜酚体外抗HP（Helicobacter pylori, HP）的作用。分别采用95%乙醇和自来水提取生姜中抗HP的成分，以阿莫西林为阳性对照，以溶剂50% PEG400和无菌水为空白对照，体外法测定生姜提取物和标准品6-姜酚对HP的抑菌作用的最小抑菌浓度（MIC）。生姜醇提物对HP的MIC为1.00 mg/mL，6-姜酚的MIC为0.02 mg/mL，生姜水提物对HP在体外无抑菌作用。6-姜酚是生姜对HP的抑菌作用的主要活性成分之一

Abstract:

Study on the in vitro anti-HP (helicobacter pylori) effect of 6-gingerol in the gingerols of ginger. Use ethylalcohol 95% and tap water to collect gingerols contained in ginger with amoxicillin as the positive control and 50% PEG400 as the blank control, and test the Minimal Inhibitory Concentration (MIC) concerning the in vitro anti-HP effect of 6-gingerol in the gingerols of ginger. In respect of the in vitro anti-HP effect, The MIC of the ethanol extract of ginger is 1.00 mg/mL, the 6-gingerol 0.02 mg/mL. The aqueous extract of ginger has no antibacterial effect in vitro. The bacteriostatic active material contained in the ginger is 6-gingerol in the gingerols.