离子液中蔗渣纤维素的硫酸酯化及抑菌效果研究

Study on the Sulfation of Bagasse Cellulose in Ionic Liquid and Antibacterial Activity of Sulfated Cellulose

摘要:

从蔗渣中分离出蔗渣纤维素（BC），以离子液[BMIM]Cl为反应介质对BC进行均相硫酸酯化得到蔗渣纤维素硫酸酯（BCS），采用13C NMR光谱对产物BCS进行结构表征，通过体外抑菌试验考察BCS的抗菌活性。结果表明，BCS结构中硫酸酯取代基分布随反应时间的变化而不同，硫酸酯化取代首先发生在C6位，然后在C2位、C3位；BCS对大肠杆菌和金黄色葡萄球菌均有一定的抑制作用，抑菌圈直径随BCS浓度的升高而增大。

Abstract:

Bagasse cellulose sulfate (BCS) was achieved via homogeneous sulfation of Bagasse Cellulose (BC) in ionic liquid [BMIM]Cl and structurally elucidated by 13C NMR. It was found that the substituent distributions of sulfate differed with the reaction time, firstly occurring in C6 place, and then in C2 and C3 places. In vitro investigation of the antibacterial activities of BCS showed that BCS could inhibit Escherichia coli and Staphylococcus aurous. Its antibacterial activity would be improved by increasing the BC concentration.