尿苷产生菌枯草芽孢杆菌Tc142分批发酵动力学研究

Study on Batch Fermentation Kinetics of a Uridine Producing Strain Bacillus subtilis Tc142

摘要:

通过建立菌体生长、产物形成和基质消耗的动力学模型，并应用MATLAB软件进行模型拟合分析，对枯草芽孢杆菌Tc142(6-Aur+2-Tur+Upase-)5 L罐尿苷分批发酵实验数据进行分析，建立尿苷分批发酵动力学模型。结果是拟合模型能较好地反映尿苷产生菌Tc142的分批发酵过程。结论是以发酵动力学为指导，应用Matlab分析方法对尿苷发酵动力学模型进行拟合，其结果与实验结果相符。

Abstract:

The kinetic model of uridine batch fermentation by Bacillus subtilis Tc142 (6-Aur+2-Tur+Upase-) in 5 L auto-control fermentation reactor was established by investigating the cell growth, uridine production and substrate consumption with Matlab software. The results showed that the model successfully simulated the batch kinetics of Tc142 for uridine production.