白底辐肛参多糖的抗凝血特性研究

Blood Anticoagulation Activity of Polysaccharides from Actinopyga mauritiana

摘要:

对昆明小鼠和新西兰兔进行不同剂量的白底辐肛参多糖AMP的注射喂养及空白试验，然后用断尾法测定小鼠的出血时间和凝血时间，并测定新西兰兔耳静脉血静脉凝血时间，数据经统计处理、方差分析和t检验后，得出AMP具有抗凝血作用，能够显著延长凝血时间。

Abstract:

Kunming mice and New Zealand rabbits were feeding with different dosage of Actinopyga mauritiana (AMP) by injection. Then the bleeding time and clotting time (CT) of mice were determined by cutting off their tails. The CT of the venous blood of New Zealand rabbit ear was also detected. Results showed that AMP had high blood anticoagulation activity, which cloud significantly prolong the CT.