海绵生物是种类繁多的共生体,其生存环境复杂、代谢途径独特，其次生代谢产物丰富多样。目前，海绵生物活性肽的研究极为活跃。本文在分析海绵生物活性肽分子结构的基础上，综述了从海绵中发现的肽具有各种生物活性，包括抗肿瘤活性、抗病毒活性、抗菌活性以及其它很多种不同的活性。指出海绵动物是一个极大的药物库，展望了海绵生物活性肽的应用前景。

Marine sponge is a kind of symbionts with many species. It grows in a very complicated environment with a very special route of metabolism so there are abundant metabolites. The study on bioactive peptides from marine sponge is up and doing now. The analysis of the structure of bioactive peptide from marine sponge, the bioactivities of marine sponge, such as anti-tumour, anti-virus, anti-bacteria and so on, were reviewed. It was pointed out that marine sponge is an infinite storeroom of medicine. And the prospect of the application of bioactive peptides form marine sponge was viewed.