葛根煎剂对四氧嘧啶致糖尿病小鼠血糖及其并发症的影响

Effects of Pueraria lobata on Blood Sugar and Complications of Alloxan-induced Diabetes Mice

摘要:

以四氧嘧啶致小鼠建立糖尿病模型，经葛根煎剂灌胃，连续35 d，每周测定空腹血糖和体重；小鼠在灌胃结束后，断头处死，分别取其胰腺和肾脏做切片进行检查。结果显示：葛根煎剂对糖尿病模型小鼠空腹血糖水平有一定的降低作用，但作用强度较弱；能改善小鼠体质的作用；对肾病并发症有较好的疗效，对被破坏的胰岛细胞有恢复和修复作用。

Abstract:

A rat model of alloxan-induced diabetes was intragastrically administered with Pueraria lobata for 35 days. And the blood sugar and weight of the rats were detected once a week. After the intragastrical administration, the rats were killed and their kidneys and pancreas were sliced up for further investigation. Results showed that the Pueraria lobata extract had relative low capability of reducing the blood sugar, while could improve the constitution of the rats. Besides, the Pueraria lobata extract showed better curative effect of kidney complications of the diabetes rats and could repair the alloxan-destructed pancreas islet cells.