为使用经济、省时地探讨白皮杉醇（Pic）的促氧化作用，本研究以邻苯二胺为原料，采用水热法合成了黄绿色荧光的碳量子点（CDs），通过紫外可见分光光度计、荧光分光光度计、透射电镜、傅里叶红外光谱仪对CDs进行表征，同时研究了其在不同温度、pH、离子强度和紫外照射时间下的稳定性，最后研究了Pic在Cu2+催化下对CDs荧光的淬灭作用及其促氧化作用的量效关系。结果表明：该CDs在水溶液中最佳发射波长为570 nm，最佳激发波长为385 nm，尺寸约为7.4 nm，表面具有酰胺键等官能团；并且其有良好的抗光漂白性，对温度和离子强度不敏感，在pH 5~10内，有良好的发光性；在100 μmol/L Cu2+条件下，Pic在浓度为1.5~12.5 μmol/L时，荧光探针的淬灭程度与Pic浓度成线性关系，而当Pic浓度高于12.5 μmol/L时，体系的荧光下降趋于平缓，促氧化效果不再明显。本研究可为Pic作为功能性食品的应用提供理论依据。

In order to investigate the pro-oxidative activity of paclitaxel (Pic) in a cost-effective and time-saving manner, this study used o-phenylenediamine as the raw material for thermal synthesis of the yellow-green fluorescent carbon quantum dots (CDs). Then the CDs were characterized by UV-vis absorption spectrophotometry, fluorescence spectrophotometry, transmission electron microscopy (TEM) and Fourier transform infrared spectroscopy (FT-IR), with their stability at different temperatures, pHs, ionic strengths, and exposure time lengths also studied. Finally, the Cu2+-catalyzed quenching effect of Pic on CDs fluorescence and the dose-response relationship were investigated. The results revealed that the CDs in aqueous solution had the optimum emission wavelength of 570 nm and optimum excitation wavelength of 385 nm, with an average diameter of 7.4 nm and a surface rich in functional groups such as amide bonds. The CDs exhibited strong resistance to photobleaching, low sensitivity to temperature and ionic strength, and good luminescence in pH 5~10. In the presence of Cu2+ at 100 μmol/L, the degree of fluorescence quenching was linear with the concentration of piceatannol in the range of 1.5~12.5 μmol/L. When the concentration of piceatannol was higher than 12.5 μmol/L, the decrease in the system’s fluorescence approached a plateau while the pro-oxidative effect of Pic was no longer obvious. This study can provide a theoretical basis for the practical application of piceatannol as a functional food.

国家重点研发计划项目（2018YFD0400600）